Phytochemical and Molecular Docking Studies on Indigenous Herbs Glycyrrhiza glabra, Terminalia chebula and Hamdard joshanda
نویسندگان
چکیده
Background: Glycyrrhiza glabra, Terminalia chebula and Hamdard joshanda is used as a traditional home medicine in developing countries that easily available for lesser cost with no side effects. These decoctions made record pandemic have found efficacious Covid-19 patients RTI addition to Dengue Malarial fever. Our study aimed explore the qualitative well quantitative potential medicines such through phytochemical GC-MS analytical technique were conducted finding all chemical constituents these herbal medicines. Docking studies carried out between receptors of crystal structure SARS coronavirus, Lung Cancer Mycobacterium tuberculosis proteins. Materials Methods: The presence various phytochemicals, total phenolic flavonoid content determined by standard procedure. was investigated using coronavirus protease modeling (PDB ID: 3SN8), Protein 6JZ0) protein 4FDO). Results: chromatogram showed 26, 18 23 peaks revealed phytoconstituents present chebula, respectively. Total contents 1.95, 1.88, 1.55, 0.66, 0.56, 0.49 mg/ml, exhibited moderate higher efficacy against Covid-19, Tuberculosis cancer. However, several more vivo vitro research needs investigate their molecular system or any other significance unused bioactive substance human relapse. Conclusion: been confirmed be safe consumption would also suggest its direct attaining proven benefits.
منابع مشابه
Studies on Flowability, Compressibility and In-vitro Release of Terminalia Chebula Fruit Powder Tablets
The dried fruit of Terminalia chebula is widely used for its laxative properties. The objective of the present study was to examine the flowability and compressibility of Terminalia chebula fruit powder, subsequently developing its tablet formulations by utilizing wet granulation and direct compression technology. Initial studies on flowability and compressibility revealed that the fruit powder...
متن کاملStudies on Flowability, Compressibility and In-vitro release of Terminalia Chebula Fruit Powder Tablets
The dried fruit of Terminalia chebula is widely used for its laxative properties. The objective of the present study was to examine the flowability and compressibility of Terminalia chebula fruit powder, subsequently developing its tablet formulations by utilizing wet granulation and direct compression technology. Initial studies on flowability and compressibility revealed that the fruit powder...
متن کاملStudies on Flowability, Compressibility and In-vitro Release of Terminalia Chebula Fruit Powder Tablets
The dried fruit of Terminalia chebula is widely used for its laxative properties. The objective of the present study was to examine the flowability and compressibility of Terminalia chebula fruit powder, subsequently developing its tablet formulations by utilizing wet granulation and direct compression technology. Initial studies on flowability and compressibility revealed that the fruit powder...
متن کاملStudies on Flowability, Compressibility and In-vitro release of Terminalia Chebula Fruit Powder Tablets
The dried fruit of Terminalia chebula is widely used for its laxative properties. The objective of the present study was to examine the flowability and compressibility of Terminalia chebula fruit powder, subsequently developing its tablet formulations by utilizing wet granulation and direct compression technology. Initial studies on flowability and compressibility revealed that the fruit powder...
متن کاملGlycyrrhiza glabra and Glycyrrhiza echinata — Sources of Low Hemotoxic Saponins
1 Department of Pharmaceutical Botany, Faculty of Pharmacy, “V. Babeș” University of Medicine and Pharmacy, Timișoara 2 Department of Biochemistry, “V. Babeș” University of Medicine and Pharmacy, Timișoara 3 Department of Toxicology, Faculty of Pharmacy, “V. Babeș” University of Medicine and Pharmacy, Timișoara 4 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, “V. Babeș” University...
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ژورنال
عنوان ژورنال: International journal of pharmaceutical investigation
سال: 2022
ISSN: ['2230-9713', '2230-973X']
DOI: https://doi.org/10.5530/ijpi.2022.1.2